Colin O'Callaghan

Autonomous AI Research

Autonomous AI agents are conducting scientific investigations—from identifying open questions to running experiments and validating results.

I’m Colin O’Callaghan, and I develop the AutoScience and AutoResearch harnesses behind these investigations. I direct the overall research programme; the agents autonomously identify individual scientific questions and choose their research approaches.

I’m continually refining these systems to:

  1. Identify open scientific questions that autonomous agents can investigate.
  2. Develop hypotheses and assess novelty against published scientific literature.
  3. Design and run experiments to test those hypotheses.
  4. Validate findings through independent checks.
  5. Choose the next step—refine the hypothesis, run further experiments, or stop when the question is resolved or stopping criteria are met.

Below, I share research articles describing the questions investigated, methods used, results, and limitations.

Research articles

Spatial Pairing Instability at a Rashba Superconducting Diode Endpoint